Hello @flguy welcome to AS. Now I could get deep about the volume you should listen at...but try this to keep it simple...get a decibel meter app for your cell phone be it iPhone or android. Set up your monitors around 80% (if your speakers aren’t professional the louder you turn them up the more hiss you will probably hear) of the volume and slowly tweak the volume from your audio interface starting at 0 til you get around 75 to 85 on your decibel meter. Depending on your room, speakers and your ears try to “feel” what’s comfortable for you. Protecting your ears from damage to extreme volumes is something most musicians don’t treat seriously enough. Your ears will thank you in the long run!

As far as lifting up the speakers it should be at ear level and in a triangle relative to where you will be sitting centered
and turned inward to your ears. Left toward left ear, right toward right ear. It doesn’t hurt to have them sitting on pads designed for the speaker as well. But seeing that you have a relatively prosumer set of equipment all my suggestions are up to you.

As far as the Focusrite interface here is a video that I deem worthy of getting you started and on the right path. Hope this helps.

Now make some good music!