Ableton Live, Reaper. Studio one is very nice for noobies imo. Tried everything, cant' stand Cubase 5 workflow or window management, Sonar x1 was...
Do as a few other have said, but a while ago I completey removed all "extra" plug ins. Stuff like: Izotope Trash, Redline Reverb/Eq, Massive,...
Separate names with a comma.