you can start by showing middle finger to Windows 10,
perform clean install of let's say Windows 7, install and setup everything you need, then physically unplug internet and you're good to go for 10 years at least,

speaking of audio interface, high-end gear like RME HDSPe AIO will offer solid drivers, hardware-accelerated ASIO DSP,
for playback and mixing, it will allow for more complex audio stuff happen at lower latency without dropouts